Do not drive or perform hazardous tasks if affected. Norco may cause drowsiness which may impair reaction skills and affect your ability to drive or operate machinery (related to the hydrocodone component).When the time comes to discontinue Norco, your doctor will advise you on how to taper it down. Norco can be addictive and may cause withdrawal symptoms if abruptly discontinued do not stop suddenly. Do not increase the dosage without his or her advice. Norco should only be used for short periods unless the pain being treated is caused by a terminal condition.However, the hydrocodone component is potentially addictive and may cause drowsiness. Norco contains acetaminophen and hydrocodone and may be used for the treatment of moderate-to-moderately severe pain.Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. Accidental ingestion by children may be fatal. May interact with several other drugs including those metabolized by the cytochrome p450 3A4 enzymes such as erythromycin, ketoconazole, and ritonavir, which may increase plasma concentrations of Norco.Rarely, adrenal insufficiency or serious skin reactions may occur. May not be suitable for some people including those with pre-existing respiratory disease bowel blockages or problems head injuries liver, kidney, or thyroid disease difficulty urinating a history of seizures, or drug abuse.The risk is highest when acetaminophen has been taken at dosages greater than 4000 mg/day or too frequently throughout the day. Rarely, liver failure has been reported (related to the acetaminophen component).This means that the same dosage may no longer provide the same pain-relieving effect. Tolerance may develop if Norco is taken for long periods (relates to the hydrocodone component).Patients and their caregivers must be counseled with every prescription on safe use, serious risks, storage, and disposal of Norco. The FDA requires a REMS (Risk Evaluation and Mitigation Strategy) for Norco which means the drug company that supplies these products must make REMS-compliant education programs available to healthcare providers.The duration of effect of the acetaminophen component is shorter than that of the hydrocodone component.Two different strengths of Norco exist, 7.5mg hydrocodone/325mg of acetaminophen, and 10mg of hydrocodone/325mg acetaminophen.Babies born to mothers who have been taken Norco may suffer from withdrawal symptoms. Norco should only be taken at the minimum effective dosage for the shortest possible time. May be misused or sought after by drug addicts. Risk of addiction, dependence, and withdrawal reactions (hydrocodone component) people with psychiatric disorders or a history of drug abuse are at the greatest risk.Use of concomitant drugs that also cause respiratory depression or sedation (such as benzodiazepines or muscle relaxants), alcohol, or use in people with pre-existing respiratory disease may further increase the risk of respiratory depression. Rarely, serious, life-threatening, breathing problems (hydrocodone component).Alcohol should be avoided as it may enhance drowsiness. Drowsiness may impair reaction skills and affect a person's ability to drive or operate machinery (hydrocodone component).Stomach upsets, including nausea, vomiting, and constipation shortness of breath dizziness low blood pressure and headache (hydrocodone component).If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Norco is available as a generic under the name acetaminophen/hydrocodone.The combination is more effective than either drug alone.Norco should be reserved for more severe types of pain, such as that caused by cancer. Effective for the management of moderate to moderately severe pain unresponsive to other non-narcotic treatment options.Norco belongs to the group of medicines known as combination narcotic analgesics. Hydrocodone binds to specific receptors known as mu opioid receptors and blocks pain signals on their way to the brain. Experts aren't sure exactly how acetaminophen works but suspect it blocks a specific type of cyclo-oxygenase (COX) enzyme, located mainly in the brain.
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